The Division of Endocrinology at Harbor-UCLA provides a very active clinical and basic research environment with four major focus groups. The Reproductive Biology Group areas of interest include reproductive endocrinology, including hormonal control of testicular cell cycle events, control of germ cell apoptosis, genetic control of meiosis initiation, ethnic differences in androgen metabolism, male contraceptive development, new methods of androgen delivery, androgen receptor physiology, CNS dysfunction in Klinefelter’s Syndrome, and reproductive dysfunction with aging; The Intermediary Metabolism/Diabetes Group focuses on stable isotopic assessments of glucose, amino acid, fatty acid and androgen metabolism; regulation of insulin release in vitro; childhood obesity and development of new techniques for diagnosis of hypoglycemic states. A third group focuses on Thyroid Cancer, Autoimmune Thyroid Disease and the mechanisms of Graves’ ophthalmopathy. A fourth group focuses on the study of Sleep/Endocrinology. A detailed description of each investigator’s interests is provided at our Faculty’s site.