The Biomedical Mass Spectrometery Facility
The Biomedical Mass Spectrometry Lab supports clinical research projects in clinical nutrition and metabolic research.
Biomedical Mass Spectrometry Facility Unit Resources
- Three gas-liquid chromatograph/mass spectrometer (GC/MS) systems, two of them are HP Mass Selective Detector (MSD) Systems (Models 5971A/5973A)
- A Finnegan Delta-S isotope ratio mass spectrometer (IRMS) used for breath CO2 analyses, and hydrogen/oxygen analyses for the doubly labeled water method of determining energy expenditure.
- ThermoQuest LCQdeca, this is a high pressure liquid chromatography/mass spectrometer (LC/MS) unit with the capability of a tandem mass spectrometer. The LCQ is used for small peptide quantitation sequence analysis and provides analytical support for investigators interested in clinical proteomics.
Services Available to GCRC or LAbioMed Research Protocols
- Sample purification and preparation
- Derivatization of substrate
- Quantitative and qualitative analysis by GC/MS, IRMS and LC/MS
- Consultation on technical problems related to instrumentation and sample preparation
- In support of projects approved by local CTSI affiliates, mass spectrometry services are also provided to: University of Southern California’s GCRC, King-Drew Medical Center, University of California at Los Angeles (Center for Health Sciences Campus), University of California at Irvine and the Cedars-Sinai Medical Center.